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However, despite this structural resemblance to other GPCRs, the sequence of the class B 7TMD is devoid of the consensus sequence motifs that typify the class A GPCRs (e.g., rhodopsin and adrenergic receptors)
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[2] It usually lasts only a few days, and while it often resolves on its own, it can still be uncomfortable and disruptive if not addressed
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